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Control of DNA minor groove width and Fis protein binding by the purine 2-amino group

The width of the DNA minor groove varies with sequence and can be a major determinant of DNA shape recognition by proteins. For example, the minor groove within the center of the Fis–DNA complex narrows to about half the mean minor groove width of canonical B-form DNA to fit onto the protein surface...

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Detalles Bibliográficos
Autores principales: Hancock, Stephen P., Ghane, Tahereh, Cascio, Duilio, Rohs, Remo, Di Felice, Rosa, Johnson, Reid C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3711457/
https://www.ncbi.nlm.nih.gov/pubmed/23661683
http://dx.doi.org/10.1093/nar/gkt357