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Identification of a Lifespan Extending Mutation in the Schizosaccharomyces pombe Cyclin Gene clg1 (+) by Direct Selection of Long-Lived Mutants
Model organisms such as budding yeast, worms and flies have proven instrumental in the discovery of genetic determinants of aging, and the fission yeast Schizosaccharomyces pombe is a promising new system for these studies. We devised an approach to directly select for long-lived S. pombe mutants fr...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Public Library of Science
2013
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3711543/ https://www.ncbi.nlm.nih.gov/pubmed/23874875 http://dx.doi.org/10.1371/journal.pone.0069084 |