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Characterization of a silent sesquiterpenoid biosynthetic pathway in Streptomyces avermitilis controlling epi‐isozizaene albaflavenone biosynthesis and isolation of a new oxidized epi‐isozizaene metabolite

The genome‐sequenced, Gram‐positive bacterium Streptomyces avermitilis harbours an orthologue (SAV_3032) of the previously identified epi‐isozizaene synthase (SCO5222) in Streptomyces coelicolor A3(2). The sav3032 is translationally coupled with the downstream sav3031 gene encoding the cytochrome P4...

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Detalles Bibliográficos
Autores principales: Takamatsu, Satoshi, Lin, Xin, Nara, Ayako, Komatsu, Mamoru, Cane, David E, Ikeda, Haruo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3711710/
https://www.ncbi.nlm.nih.gov/pubmed/21342464
http://dx.doi.org/10.1111/j.1751-7915.2010.00209.x