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TWEAK promotes exercise intolerance by decreasing skeletal muscle oxidative phosphorylation capacity

BACKGROUND: Proinflammatory cytokine tumor necrosis factor (TNF)-like weak inducer of apoptosis (TWEAK) and its receptor Fn14 are the major regulators of skeletal muscle mass in many catabolic conditions. However, their role in muscle metabolism remains largely unknown. In the present study, we inve...

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Detalles Bibliográficos
Autores principales: Sato, Shuichi, Ogura, Yuji, Mishra, Vivek, Shin, Jonghyun, Bhatnagar, Shephali, Hill, Bradford G, Kumar, Ashok
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3711790/
https://www.ncbi.nlm.nih.gov/pubmed/23835416
http://dx.doi.org/10.1186/2044-5040-3-18