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Transient oscillatory dynamics of interferon beta signaling in macrophages

BACKGROUND: Interferon-beta (IFN-beta) activates the immune response through the type I IFN signaling pathway. IFN-beta is important in the response to pathogen infections and is used as a therapy for Multiple Sclerosis. The mechanisms of self-regulation and control of this pathway allow precise and...

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Detalles Bibliográficos
Autores principales: Pertsovskaya, Inna, Abad, Elena, Domedel-Puig, Núria, Garcia-Ojalvo, Jordi, Villoslada, Pablo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3711797/
https://www.ncbi.nlm.nih.gov/pubmed/23837526
http://dx.doi.org/10.1186/1752-0509-7-59