Cooperative Roles of SDF-1α and EGF Gradients on Tumor Cell Migration Revealed by a Robust 3D Microfluidic Model

Chemokine-mediated directed tumor cell migration within a three dimensional (3D) matrix, or chemoinvasion, is an important early step in cancer metastasis. Despite its clinical importance, it is largely unknown how cytokine and growth factor gradients within the tumor microenvironment regulate chemo...

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Detalles Bibliográficos
Autores principales: Kim, Beum Jun, Hannanta-anan, Pimkhuan, Chau, Michelle, Kim, Yoon Soo, Swartz, Melody A., Wu, Mingming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3711811/
https://www.ncbi.nlm.nih.gov/pubmed/23869217
http://dx.doi.org/10.1371/journal.pone.0068422

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3711811/
https://www.ncbi.nlm.nih.gov/pubmed/23869217
http://dx.doi.org/10.1371/journal.pone.0068422

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