Glutamatergic Dysbalance and Oxidative Stress in In Vivo and In Vitro Models of Psychosis Based on Chronic NMDA Receptor Antagonism

BACKGROUND: The psychotomimetic effects of N-methyl-D-aspartate (NMDA) receptor antagonists in healthy humans and their tendency to aggravate psychotic symptoms in schizophrenic patients have promoted the notion of altered glutamatergic neurotransmission in the pathogenesis of schizophrenia. METHODS...

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Detalles Bibliográficos
Autores principales: Genius, Just, Geiger, Johanna, Dölzer, Anna-Lena, Benninghoff, Jens, Giegling, Ina, Hartmann, Annette M., Möller, Hans-Jürgen, Rujescu, Dan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3711936/
https://www.ncbi.nlm.nih.gov/pubmed/23869202
http://dx.doi.org/10.1371/journal.pone.0059395

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3711936/
https://www.ncbi.nlm.nih.gov/pubmed/23869202
http://dx.doi.org/10.1371/journal.pone.0059395

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