The genetics of infectious disease susceptibility: has the evidence for epistasis been overestimated?

Interactions amongst genes, known as epistasis, are assumed to make a substantial contribution to the genetic variation in infectious disease susceptibility, but this claim is controversial. Here, we focus on the debate surrounding the evolutionary importance of interactions between resistance loci...

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Detalles Bibliográficos
Autores principales: Hall, Matthew D, Ebert, Dieter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Opinion
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3711976/
https://www.ncbi.nlm.nih.gov/pubmed/23855805
http://dx.doi.org/10.1186/1741-7007-11-79

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3711976/
https://www.ncbi.nlm.nih.gov/pubmed/23855805
http://dx.doi.org/10.1186/1741-7007-11-79

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