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The genetics of infectious disease susceptibility: has the evidence for epistasis been overestimated?
Interactions amongst genes, known as epistasis, are assumed to make a substantial contribution to the genetic variation in infectious disease susceptibility, but this claim is controversial. Here, we focus on the debate surrounding the evolutionary importance of interactions between resistance loci...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2013
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3711976/ https://www.ncbi.nlm.nih.gov/pubmed/23855805 http://dx.doi.org/10.1186/1741-7007-11-79 |