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Synthesis and structure−activity relationship of 8-substituted protoberberine derivatives as a novel class of antitubercular agents
BACKGROUND: The emergence of multi-drug resistant tuberculosis (MDR-TB) has heightened the need for new chemical classes and innovative strategies to tackle TB infections. It is urgent to discover new classes of molecules without cross-resistance with currently used antimycobacterial drugs. RESULTS:...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3712002/ https://www.ncbi.nlm.nih.gov/pubmed/23837573 http://dx.doi.org/10.1186/1752-153X-7-117 |