Molecular topography of the MED12-deleted region in smooth muscle tumors: a possible link between non-B DNA structures and hypermutability

BACKGROUND: Deletions of the gene encoding mediator subcomplex 12 (MED12) in human smooth muscle tumors rank among the most frequent genomic alterations in human tumors at all. In a minority of these cases, small deletions are found. In an attempt to delineate key features of the deletions aimed at...

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Detalles Bibliográficos
Autores principales: Markowski, Dominique Nadine, Nimzyk, Rolf, Belge, Gazanfer, Löning, Thomas, Helmke, Burkhard Maria, Bullerdiek, Jörn
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3712005/
https://www.ncbi.nlm.nih.gov/pubmed/23738817
http://dx.doi.org/10.1186/1755-8166-6-23

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3712005/
https://www.ncbi.nlm.nih.gov/pubmed/23738817
http://dx.doi.org/10.1186/1755-8166-6-23

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