The cAMP effector EPAC activates Elk1 transcription factor in prostate smooth muscle, and is a minor regulator of α1-adrenergic contraction

BACKGROUND: Prostate smooth muscle tone is regulated by α1-adrenoceptor-induced contraction and cAMP-mediated relaxation. EPAC is an effector of cAMP, being involved in smooth muscle relaxation and cell cycle control outside the lower urinary tract. Here, we investigated the expression and function...

Descripción completa

Detalles Bibliográficos
Autores principales: Hennenberg, Martin, Strittmatter, Frank, Schmetkamp, Henning, Rutz, Beata, Walther, Sebastian, Stief, Christian G, Gratzke, Christian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3712007/
https://www.ncbi.nlm.nih.gov/pubmed/23815815
http://dx.doi.org/10.1186/1423-0127-20-46

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3712007/
https://www.ncbi.nlm.nih.gov/pubmed/23815815
http://dx.doi.org/10.1186/1423-0127-20-46

Ejemplares similares