The cAMP effector EPAC activates Elk1 transcription factor in prostate smooth muscle, and is a minor regulator of α1-adrenergic contraction

BACKGROUND: Prostate smooth muscle tone is regulated by α1-adrenoceptor-induced contraction and cAMP-mediated relaxation. EPAC is an effector of cAMP, being involved in smooth muscle relaxation and cell cycle control outside the lower urinary tract. Here, we investigated the expression and function...

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Detalles Bibliográficos
Autores principales: Hennenberg, Martin, Strittmatter, Frank, Schmetkamp, Henning, Rutz, Beata, Walther, Sebastian, Stief, Christian G, Gratzke, Christian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3712007/
https://www.ncbi.nlm.nih.gov/pubmed/23815815
http://dx.doi.org/10.1186/1423-0127-20-46

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