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Signaling pathway switch in breast cancer

Next generation sequencing studies have drawn the general landscape of breast cancers and identified hundreds of new, actual therapeutic targets. Two major signaling pathways seem to be altered in a vast proportion of breast cancers. The PI3 kinase/AKT pathway is activated and the JUN/MAPK pathway i...

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Detalles Bibliográficos
Autores principales: Guille, Arnaud, Chaffanet, Max, Birnbaum, Daniel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3712008/
https://www.ncbi.nlm.nih.gov/pubmed/23805779
http://dx.doi.org/10.1186/1475-2867-13-66