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Environmentally Induced Transgenerational Epigenetic Reprogramming of Primordial Germ Cells and the Subsequent Germ Line

A number of environmental factors (e.g. toxicants) have been shown to promote the epigenetic transgenerational inheritance of disease and phenotypic variation. Transgenerational inheritance requires the germline transmission of altered epigenetic information between generations in the absence of dir...

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Detalles Bibliográficos
Autores principales: Skinner, Michael K., Haque, Carlos Guerrero-Bosagna M., Nilsson, Eric, Bhandari, Ramji, McCarrey, John R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3712023/
https://www.ncbi.nlm.nih.gov/pubmed/23869203
http://dx.doi.org/10.1371/journal.pone.0066318