Ku70 Functions in Addition to Nonhomologous End Joining in Pancreatic β-Cells: A Connection to β-Catenin Regulation

The genesis of β-cells predominantly occurs through self-replication; therefore, understanding the regulation of cell proliferation is essential. We previously showed that the lack of nonhomologous end joining (NHEJ) DNA repair factor ligase IV leads to an accumulation of DNA damage that permanently...

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Detalles Bibliográficos
Autores principales: Tavana, Omid, Puebla-Osorio, Nahum, Kim, Jiseong, Sang, Mei, Jang, Stella, Zhu, Chengming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Diabetes Association 2013
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3712041/
https://www.ncbi.nlm.nih.gov/pubmed/23474484
http://dx.doi.org/10.2337/db12-1218

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3712041/
https://www.ncbi.nlm.nih.gov/pubmed/23474484
http://dx.doi.org/10.2337/db12-1218

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