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Ku70 Functions in Addition to Nonhomologous End Joining in Pancreatic β-Cells: A Connection to β-Catenin Regulation
The genesis of β-cells predominantly occurs through self-replication; therefore, understanding the regulation of cell proliferation is essential. We previously showed that the lack of nonhomologous end joining (NHEJ) DNA repair factor ligase IV leads to an accumulation of DNA damage that permanently...
Autores principales: | Tavana, Omid, Puebla-Osorio, Nahum, Kim, Jiseong, Sang, Mei, Jang, Stella, Zhu, Chengming |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Diabetes Association
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3712041/ https://www.ncbi.nlm.nih.gov/pubmed/23474484 http://dx.doi.org/10.2337/db12-1218 |
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