Next Generation Sequencing Reveals the Association of DRB3*02:02 With Type 1 Diabetes

The primary associations of the HLA class II genes, HLA-DRB1 and HLA-DQB1, and the class I genes, HLA-A and HLA-B, with type 1 diabetes (T1D) are well established. However, the role of polymorphism at the HLA-DRB3, HLA-DRB4, and HLA-DRB5 loci remains unclear. In two separate studies, one of 500 subj...

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Detalles Bibliográficos
Autores principales: Erlich, Henry A., Valdes, Ana Maria, McDevitt, Shana L., Simen, Birgitte B., Blake, Lisbeth A., McGowan, Kim R., Todd, John A., Rich, Stephen S., Noble, Janelle A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Diabetes Association 2013
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3712046/
https://www.ncbi.nlm.nih.gov/pubmed/23462545
http://dx.doi.org/10.2337/db12-1387

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3712046/
https://www.ncbi.nlm.nih.gov/pubmed/23462545
http://dx.doi.org/10.2337/db12-1387

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