In Vivo JNK Activation in Pancreatic β-Cells Leads to Glucose Intolerance Caused by Insulin Resistance in Pancreas

Insulin resistance is a key condition in the development of type 2 diabetes. It is well established that exacerbated Jun NH(2)-terminal kinase (JNK) activity is involved in promoting insulin resistance in peripheral insulin-target tissues; however, this involvement is less documented in pancreatic β...

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Detalles Bibliográficos
Autores principales: Lanuza-Masdeu, Jordi, Arévalo, M. Isabel, Vila, Cristina, Barberà, Albert, Gomis, Ramon, Caelles, Carme
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Diabetes Association 2013
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3712047/
https://www.ncbi.nlm.nih.gov/pubmed/23349497
http://dx.doi.org/10.2337/db12-1097

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3712047/
https://www.ncbi.nlm.nih.gov/pubmed/23349497
http://dx.doi.org/10.2337/db12-1097

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