Hyperglycemia Mediates a Shift From Cap-Dependent to Cap-Independent Translation Via a 4E-BP1–Dependent Mechanism

Diabetes and its associated hyperglycemia induce multiple changes in liver function, yet we know little about the role played by translational control of gene expression in mediating the responses to these conditions. Here, we evaluate the hypothesis that hyperglycemia-induced O-GlcNAcylation of the...

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Detalles Bibliográficos
Autores principales: Dennis, Michael D., Shenberger, Jeffrey S., Stanley, Bruce A., Kimball, Scot R., Jefferson, Leonard S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Diabetes Association 2013
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3712054/
https://www.ncbi.nlm.nih.gov/pubmed/23434932
http://dx.doi.org/10.2337/db12-1453

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3712054/
https://www.ncbi.nlm.nih.gov/pubmed/23434932
http://dx.doi.org/10.2337/db12-1453

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