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Hyperglycemia Mediates a Shift From Cap-Dependent to Cap-Independent Translation Via a 4E-BP1–Dependent Mechanism
Diabetes and its associated hyperglycemia induce multiple changes in liver function, yet we know little about the role played by translational control of gene expression in mediating the responses to these conditions. Here, we evaluate the hypothesis that hyperglycemia-induced O-GlcNAcylation of the...
Autores principales: | Dennis, Michael D., Shenberger, Jeffrey S., Stanley, Bruce A., Kimball, Scot R., Jefferson, Leonard S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Diabetes Association
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3712054/ https://www.ncbi.nlm.nih.gov/pubmed/23434932 http://dx.doi.org/10.2337/db12-1453 |
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