Concentration and Activity of the Soluble Form of the Interleukin-7 Receptor α in Type 1 Diabetes Identifies an Interplay Between Hyperglycemia and Immune Function

Soluble interleukin-7 (IL-7) receptor α (sCD127) is implicated in the pathogenesis of autoimmune diseases. We show that serum sCD127 concentrations are increased at the onset of type 1 diabetes (T1D; n = 390) as compared with concentrations in age-matched islet autoantibody–negative first-degree rel...

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Detalles Bibliográficos
Autores principales: Monti, Paolo, Brigatti, Cristina, Krasmann, Miriam, Ziegler, Anette G., Bonifacio, Ezio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Diabetes Association 2013
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3712069/
https://www.ncbi.nlm.nih.gov/pubmed/23454692
http://dx.doi.org/10.2337/db12-1726

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3712069/
https://www.ncbi.nlm.nih.gov/pubmed/23454692
http://dx.doi.org/10.2337/db12-1726

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