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Amelioration of Hypoglycemia Via Somatostatin Receptor Type 2 Antagonism in Recurrently Hypoglycemic Diabetic Rats

Selective antagonism of somatostatin receptor type 2 (SSTR2) normalizes glucagon and corticosterone responses to hypoglycemic clamp in diabetic rats. The purpose of this study was to determine whether SSTR2 antagonism (SSTR2a) ameliorates hypoglycemia in response to overinsulinization in diabetic ra...

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Detalles Bibliográficos
Autores principales: Yue, Jessica T.Y., Riddell, Michael C., Burdett, Elena, Coy, David H., Efendic, Suad, Vranic, Mladen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Diabetes Association 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3712070/
https://www.ncbi.nlm.nih.gov/pubmed/23434929
http://dx.doi.org/10.2337/db12-1523