Role of N-acetylcysteine and GSH redox system on total and active MMP-2 in intestinal myofibroblasts of Crohn's disease patients

PURPOSE: Intestinal subepithelial myofibroblasts (ISEMFs)(1) are the predominant source of matrix metalloproteinase-2 (MMP-2) in gut, and a decrease in glutathione/oxidized glutathione (GSH/GSSG) ratio, intracellular redox state index, occurs in the ISEMFs of patients with Crohn’s disease (CD). The...

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Detalles Bibliográficos
Autores principales: Romagnoli, Cecilia, Marcucci, Tommaso, Picariello, Lucia, Tonelli, Francesco, Vincenzini, Maria Teresa, Iantomasi, Teresa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2012
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3712135/
https://www.ncbi.nlm.nih.gov/pubmed/23271497
http://dx.doi.org/10.1007/s00384-012-1632-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3712135/
https://www.ncbi.nlm.nih.gov/pubmed/23271497
http://dx.doi.org/10.1007/s00384-012-1632-2

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