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Receptor for advanced glycation endproducts (RAGE) deficiency protects against MPTP toxicity

Parkinson's disease (PD) is a common neurodegenerative disorder of unknown pathogenesis characterized by the loss of nigrostriatal dopaminergic neurons. Oxidative stress, microglial activation and inflammatory responses seem to contribute to the pathogenesis. The receptor for advanced glycation...

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Detalles Bibliográficos
Autores principales: Teismann, Peter, Sathe, Kinnari, Bierhaus, Angelika, Leng, Lin, Martin, Heather L., Bucala, Richard, Weigle, Bernd, Nawroth, Peter P., Schulz, Jörg B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3712169/
https://www.ncbi.nlm.nih.gov/pubmed/22227007
http://dx.doi.org/10.1016/j.neurobiolaging.2011.12.006