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A Polymorphism Associated with Depressive Disorders Differentially Regulates Brain Derived Neurotrophic Factor Promoter IV Activity

BACKGROUND: Changes in brain derived neurotrophic factor (BDNF) expression have been associated with mood disorders and cognitive dysfunction. Transgenic models that overexpress or underexpress BDNF demonstrate similar deficits in cognition and mood. We explored the hypothesis that BDNF expression i...

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Detalles Bibliográficos
Autores principales: Hing, Benjamin, Davidson, Scott, Lear, Marrisa, Breen, Gerome, Quinn, John, McGuffin, Peter, MacKenzie, Alasdair
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3712170/
https://www.ncbi.nlm.nih.gov/pubmed/22265241
http://dx.doi.org/10.1016/j.biopsych.2011.11.030