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A Polymorphism Associated with Depressive Disorders Differentially Regulates Brain Derived Neurotrophic Factor Promoter IV Activity
BACKGROUND: Changes in brain derived neurotrophic factor (BDNF) expression have been associated with mood disorders and cognitive dysfunction. Transgenic models that overexpress or underexpress BDNF demonstrate similar deficits in cognition and mood. We explored the hypothesis that BDNF expression i...
Autores principales: | Hing, Benjamin, Davidson, Scott, Lear, Marrisa, Breen, Gerome, Quinn, John, McGuffin, Peter, MacKenzie, Alasdair |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3712170/ https://www.ncbi.nlm.nih.gov/pubmed/22265241 http://dx.doi.org/10.1016/j.biopsych.2011.11.030 |
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