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Enhancement of radiation effect using beta-lapachone and underlying mechanism

Beta-lapachone (β-Lap; 3,4-dihydro-2, 2-dimethyl-2H-naphthol[1, 2-b]pyran-5,6-dione) is a novel anti-cancer drug under phase I/II clinical trials. β-Lap has been demonstrated to cause apoptotic and necrotic death in a variety of human cancer cells in vitro and in vivo. The mechanisms underlying the...

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Detalles Bibliográficos
Autores principales: Ahn, Ki Jung, Lee, Hyung Sik, Bai, Se Kyung, Song, Chang Won
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Society for Radiation Oncology 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3712174/
https://www.ncbi.nlm.nih.gov/pubmed/23865001
http://dx.doi.org/10.3857/roj.2013.31.2.57