In vivo studies of Scn5a+/− mice modeling Brugada syndrome demonstrate both conduction and repolarization abnormalities

OBJECTIVES: We investigate the extent to which the electrocardiographic (ECG) properties of intact Scn5a+/− mice reproduce the corresponding clinical Brugada syndrome phenotype and use this model to investigate the role of conduction and repolarization abnormalities in the arrhythmogenic mechanism....

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Detalles Bibliográficos
Autores principales: Martin, Claire A., Zhang, Yanmin, Grace, Andrew A., Huang, Christopher L.-H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Churchill Livingstone 2010
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3712183/
https://www.ncbi.nlm.nih.gov/pubmed/20638671
http://dx.doi.org/10.1016/j.jelectrocard.2010.05.015

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3712183/
https://www.ncbi.nlm.nih.gov/pubmed/20638671
http://dx.doi.org/10.1016/j.jelectrocard.2010.05.015

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