Molecular Dynamics Studies on the Conformational Transitions of Adenylate Kinase: A Computational Evidence for the Conformational Selection Mechanism

Escherichia coli adenylate kinase (ADK) is a monomeric phosphotransferase enzyme that catalyzes reversible transfer of phosphoryl group from ATP to AMP with a large-scale domain motion. The detailed mechanism for this conformational transition remains unknown. In the current study, we performed long...

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Detalles Bibliográficos
Autores principales: Ping, Jie, Hao, Pei, Li, Yi-Xue, Wang, Jing-Fang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3712241/
https://www.ncbi.nlm.nih.gov/pubmed/23936827
http://dx.doi.org/10.1155/2013/628536

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3712241/
https://www.ncbi.nlm.nih.gov/pubmed/23936827
http://dx.doi.org/10.1155/2013/628536

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