Cargando…
Molecular Dynamics Studies on the Conformational Transitions of Adenylate Kinase: A Computational Evidence for the Conformational Selection Mechanism
Escherichia coli adenylate kinase (ADK) is a monomeric phosphotransferase enzyme that catalyzes reversible transfer of phosphoryl group from ATP to AMP with a large-scale domain motion. The detailed mechanism for this conformational transition remains unknown. In the current study, we performed long...
Autores principales: | Ping, Jie, Hao, Pei, Li, Yi-Xue, Wang, Jing-Fang |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi Publishing Corporation
2013
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3712241/ https://www.ncbi.nlm.nih.gov/pubmed/23936827 http://dx.doi.org/10.1155/2013/628536 |
Ejemplares similares
-
Conformational Dynamics of a Ligand-Free Adenylate Kinase
por: Song, Hyun Deok, et al.
Publicado: (2013) -
Role of Repeated
Conformational Transitions in Substrate
Binding of Adenylate Kinase
por: Lu, Jiajun, et al.
Publicado: (2022) -
Integration of Adenylate Kinase 1 with Its Peptide Conformational Imprint
por: Wu, Cheng-Hsin, et al.
Publicado: (2022) -
Ras Conformational Switching: Simulating Nucleotide-Dependent Conformational Transitions with Accelerated Molecular Dynamics
por: Grant, Barry J., et al.
Publicado: (2009) -
Modeling conformational transitions in kinases by molecular dynamics simulations: achievements, difficulties, and open challenges
por: D'Abramo, Marco, et al.
Publicado: (2014)