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The C-Type Lectin Receptor SIGNR3 Binds to Fungi Present in Commensal Microbiota and Influences Immune Regulation in Experimental Colitis

Inflammatory bowel disease is a condition of acute and chronic inflammation of the gut. An important factor contributing to pathogenesis is a dysregulated mucosal immunity against commensal bacteria and fungi. Host pattern-recognition receptors (PRRs) sense commensals in the gut and are involved in...

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Detalles Bibliográficos
Autores principales: Eriksson, Magdalena, Johannssen, Timo, von Smolinski, Dorthe, Gruber, Achim D., Seeberger, Peter H., Lepenies, Bernd
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3712271/
https://www.ncbi.nlm.nih.gov/pubmed/23882266
http://dx.doi.org/10.3389/fimmu.2013.00196