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S-nitrosylation regulates mitochondrial quality control via activation of parkin

Parkin, a ubiquitin E3 ligase of the ring between ring fingers family, has been implicated in mitochondrial quality control. A series of recent reports have suggested that the recruitment of parkin is regulated by phosphorylation. However, the molecular mechanism that activates parkin to induce mito...

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Detalles Bibliográficos
Autores principales: Ozawa, Kentaro, Komatsubara, Akira T., Nishimura, Yuhei, Sawada, Tomoyo, Kawafune, Hiroto, Tsumoto, Hiroki, Tsuji, Yuichi, Zhao, Jing, Kyotani, Yoji, Tanaka, Toshio, Takahashi, Ryosuke, Yoshizumi, Masanori
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3712319/
https://www.ncbi.nlm.nih.gov/pubmed/23857542
http://dx.doi.org/10.1038/srep02202