TRAIL induces apoptosis in oral squamous carcinoma cells: a crosstalk with oncogenic Ras regulated cell surface expression of death receptor 5

TNF-related apoptosis inducing ligand (TRAIL) induces apoptosis through its death receptors (DRs) 4 and/or 5 expressed on the surface of target cells. The selectivity of TRAIL towards cancer cells has promoted clinical evaluation of recombinant human TRAIL (rhTRAIL) and its agonistic antibodies in t...

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Detalles Bibliográficos
Autores principales: Chen, Jun-jie, Mikelis, Constantinos M., Zhang, Yaqin, Gutkind, J. Silvio, Zhang, Baolin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2013
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3712567/
https://www.ncbi.nlm.nih.gov/pubmed/23470485

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3712567/
https://www.ncbi.nlm.nih.gov/pubmed/23470485

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