Tumor-Promoting Circuits That Regulate a Cancer-Related Chemokine Cluster: Dominance of Inflammatory Mediators Over Oncogenic Alterations

Here, we investigated the relative contribution of genetic/signaling components versus microenvironmental factors to the malignancy phenotype. In this system, we took advantage of non-transformed fibroblasts that carried defined oncogenic modifications in Ras and/or p53. These cells were exposed to...

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Detalles Bibliográficos
Autores principales: Leibovich-Rivkin, Tal, Buganim, Yosef, Solomon, Hilla, Meshel, Tsipi, Rotter, Varda, Ben-Baruch, Adit
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2012
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3712671/
https://www.ncbi.nlm.nih.gov/pubmed/24213226
http://dx.doi.org/10.3390/cancers4010055

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3712671/
https://www.ncbi.nlm.nih.gov/pubmed/24213226
http://dx.doi.org/10.3390/cancers4010055

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