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Membrane Type-1 Matrix Metalloproteinase Expression in Acute Myeloid Leukemia and Its Upregulation by Tumor Necrosis Factor-α

Membrane type-1 matrix metalloproteinase (MT1-MMP) has been implicated in tumor invasion, as well as trafficking of normal hematopoietic cells, and acts as a physiologic activator of proMMP-2. In this study we examined MT1-MMP expression in primary acute myeloid leukemia (AML) cells. Because tumor n...

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Detalles Bibliográficos
Autores principales: Marquez-Curtis, Leah A., Shirvaikar, Neeta, Turner, A. Robert, Mirza, Imran, Surmawala, Amir, Larratt, Loree M., Janowska-Wieczorek, Anna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3712719/
https://www.ncbi.nlm.nih.gov/pubmed/24213464
http://dx.doi.org/10.3390/cancers4030743