Do Non-Genomically Encoded Fusion Transcripts Cause Recurrent Chromosomal Translocations?

We among others have recently demonstrated that normal cells produce “fusion mRNAs”. These fusion mRNAs do not derive from rearranged genomic loci, but rather they are derived from “early-terminated transcripts” (ETTs). Premature transcriptional termination takes place in intronic sequences that bel...

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Detalles Bibliográficos
Autores principales: Kowarz, Eric, Dingermann, Theo, Marschalek, Rolf
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2012
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3712730/
https://www.ncbi.nlm.nih.gov/pubmed/24213499
http://dx.doi.org/10.3390/cancers4041036

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3712730/
https://www.ncbi.nlm.nih.gov/pubmed/24213499
http://dx.doi.org/10.3390/cancers4041036

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