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Dynactin Subunit p150(Glued) Is a Neuron-Specific Anti-Catastrophe Factor

Regulation of microtubule dynamics in neurons is critical, as defects in the microtubule-based transport of axonal organelles lead to neurodegenerative disease. The microtubule motor cytoplasmic dynein and its partner complex dynactin drive retrograde transport from the distal axon. We have recently...

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Detalles Bibliográficos
Autores principales: Lazarus, Jacob E., Moughamian, Armen J., Tokito, Mariko K., Holzbaur, Erika L. F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3712912/
https://www.ncbi.nlm.nih.gov/pubmed/23874158
http://dx.doi.org/10.1371/journal.pbio.1001611