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Changes in the Transcriptome of the Human Endometrial Ishikawa Cancer Cell Line Induced by Estrogen, Progesterone, Tamoxifen, and Mifepristone (RU486) as Detected by RNA-Sequencing

BACKGROUND: Estrogen (E2) and progesterone (P4) are key players in the maturation of the human endometrium. The corresponding steroid hormone modulators, tamoxifen (TAM) and mifepristone (RU486) are widely used in breast cancer therapy and for contraception purposes, respectively. METHODOLOGY/PRINCI...

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Detalles Bibliográficos
Autores principales: Tamm-Rosenstein, Karin, Simm, Jaak, Suhorutshenko, Marina, Salumets, Andres, Metsis, Madis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3712916/
https://www.ncbi.nlm.nih.gov/pubmed/23874806
http://dx.doi.org/10.1371/journal.pone.0068907