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Successful Human Infection with P. falciparum Using Three Aseptic Anopheles stephensi Mosquitoes: A New Model for Controlled Human Malaria Infection

Controlled human malaria infection (CHMI) is a powerful method for assessing the efficacy of anti-malaria vaccines and drugs targeting pre-erythrocytic and erythrocytic stages of the parasite. CHMI has heretofore required the bites of 5 Plasmodium falciparum (Pf) sporozoite (SPZ)-infected mosquitoes...

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Detalles Bibliográficos
Autores principales: Laurens, Matthew B., Billingsley, Peter, Richman, Adam, Eappen, Abraham G., Adams, Matthew, Li, Tao, Chakravarty, Sumana, Gunasekera, Anusha, Jacob, Christopher G., Sim, B. Kim Lee, Edelman, Robert, Plowe, Christopher V., Hoffman, Stephen L., Lyke, Kirsten E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3712927/
https://www.ncbi.nlm.nih.gov/pubmed/23874828
http://dx.doi.org/10.1371/journal.pone.0068969