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Successful Human Infection with P. falciparum Using Three Aseptic Anopheles stephensi Mosquitoes: A New Model for Controlled Human Malaria Infection
Controlled human malaria infection (CHMI) is a powerful method for assessing the efficacy of anti-malaria vaccines and drugs targeting pre-erythrocytic and erythrocytic stages of the parasite. CHMI has heretofore required the bites of 5 Plasmodium falciparum (Pf) sporozoite (SPZ)-infected mosquitoes...
Autores principales: | Laurens, Matthew B., Billingsley, Peter, Richman, Adam, Eappen, Abraham G., Adams, Matthew, Li, Tao, Chakravarty, Sumana, Gunasekera, Anusha, Jacob, Christopher G., Sim, B. Kim Lee, Edelman, Robert, Plowe, Christopher V., Hoffman, Stephen L., Lyke, Kirsten E. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3712927/ https://www.ncbi.nlm.nih.gov/pubmed/23874828 http://dx.doi.org/10.1371/journal.pone.0068969 |
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