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Structural Basis of the Novel S. pneumoniae Virulence Factor, GHIP, a Glycosyl Hydrolase 25 Participating in Host-Cell Invasion

Pathogenic bacteria produce a wide variety of virulence factors that are considered to be potential antibiotic targets. In this study, we report the crystal structure of a novel S. pneumoniae virulence factor, GHIP, which is a streptococcus-specific glycosyl hydrolase. This novel structure exhibits...

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Detalles Bibliográficos
Autores principales: Niu, Siqiang, Luo, Miao, Tang, Jian, Zhou, Hua, Zhang, Yangli, Min, Xun, Cai, Xuefei, Zhang, Wenlu, Xu, Wenchu, Li, Defeng, Ding, Jingjin, Hu, Yonglin, Wang, Dacheng, Huang, Ailong, Yin, Yibin, Wang, Deqiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3712932/
https://www.ncbi.nlm.nih.gov/pubmed/23874703
http://dx.doi.org/10.1371/journal.pone.0068647