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Emerging Role of Calcium-Activated Potassium Channel in the Regulation of Cell Viability Following Potassium Ions Challenge in HEK293 Cells and Pharmacological Modulation

Emerging evidences suggest that Ca(2+)activated-K(+)-(BK) channel is involved in the regulation of cell viability. The changes of the cell viability observed under hyperkalemia (15 mEq/L) or hypokalemia (0.55 mEq/L) conditions were investigated in HEK293 cells expressing the hslo subunit (hslo-HEK29...

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Detalles Bibliográficos
Autores principales: Tricarico, Domenico, Mele, Antonietta, Calzolaro, Sara, Cannone, Gianluigi, Camerino, Giulia Maria, Dinardo, Maria Maddalena, Latorre, Ramon, Conte Camerino, Diana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3712936/
https://www.ncbi.nlm.nih.gov/pubmed/23874973
http://dx.doi.org/10.1371/journal.pone.0069551