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Amelioration of Liver Injury by Continuously Targeted Intervention against TNFRp55 in Rats with Acute-on-Chronic Liver Failure

BACKGROUND: Acute-on-chronic liver failure (ACLF) is an acute deterioration of established liver disease. Blocking the TNF (tumor necrosis factor)/TNFR (tumor necrosis factor receptor) 1 pathway may reduce hepatocyte apoptosis/necrosis, and subsequently decrease mortality during development of ACLF....

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Detalles Bibliográficos
Autores principales: Xu, Yumin, Wang, Hui, Bao, Shishan, Tabassam, Fazal, Cai, Wei, Xiang, Xiaogang, Zhao, Gangde, Wu, Haiqing, Gao, Ting, Li, Hai, Xie, Qing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3712937/
https://www.ncbi.nlm.nih.gov/pubmed/23874752
http://dx.doi.org/10.1371/journal.pone.0068757