The Modified Selenenyl Amide, M-hydroxy Ebselen, Attenuates Diabetic Nephropathy and Diabetes-Associated Atherosclerosis in ApoE/GPx1 Double Knockout Mice

Seleno-organic glutathione peroxidase (GPx) mimetics, including ebselen (Eb), have been tested in in vitro studies for their ability to scavenge reactive oxygen and nitrogen species, including hydrogen peroxide and peroxynitrite. In this study, we investigated the efficacies of two Eb analogues, m-h...

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Detalles Bibliográficos
Autores principales: Tan, Sih Min, Sharma, Arpeeta, Yuen, Derek Y. C., Stefanovic, Nada, Krippner, Guy, Mugesh, Govindasamy, Chai, Zhonglin, de Haan, Judy B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3712958/
https://www.ncbi.nlm.nih.gov/pubmed/23874911
http://dx.doi.org/10.1371/journal.pone.0069193

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3712958/
https://www.ncbi.nlm.nih.gov/pubmed/23874911
http://dx.doi.org/10.1371/journal.pone.0069193

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