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RNA Deep Sequencing Analysis Reveals That Nicotine Restores Impaired Gene Expression by Viral Proteins in the Brains of HIV-1 Transgenic Rats

Persons infected with HIV-1 often develop neurologic disorders despite receiving highly active anti-retroviral therapy. Although the underlying mechanism is largely undetermined, our previous RNA-seq-based study showed that the expression of many genes was altered in the central nervous system (CNS)...

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Detalles Bibliográficos
Autores principales: Cao, Junran, Wang, Shaolin, Wang, Ju, Cui, Wenyan, Nesil, Tanseli, Vigorito, Michael, Chang, Sulie L., Li, Ming D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3712985/
https://www.ncbi.nlm.nih.gov/pubmed/23874651
http://dx.doi.org/10.1371/journal.pone.0068517