Unlocked Concanavalin A Forms Amyloid-like Fibrils from Coagulation of Long-lived “Crinkled” Intermediates

Understanding the early events during amyloid aggregation processes is crucial to single out the involved molecular mechanisms and for designing ad hoc strategies to prevent and reverse amyloidogenic disorders. Here, we show that, in conditions in which the protein is positively charged and its conf...

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Detalles Bibliográficos
Autores principales: Vetri, Valeria, Leone, Maurizio, Morozova-Roche, Ludmilla A., Vestergaard, Bente, Foderà, Vito
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3712988/
https://www.ncbi.nlm.nih.gov/pubmed/23874809
http://dx.doi.org/10.1371/journal.pone.0068912

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3712988/
https://www.ncbi.nlm.nih.gov/pubmed/23874809
http://dx.doi.org/10.1371/journal.pone.0068912

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