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Inhibition of VEGF-C Modulates Distal Lymphatic Remodeling and Secondary Metastasis

Tumor-associated lymphatics are postulated to provide a transit route for disseminating metastatic cells. This notion is supported by preclinical findings that inhibition of pro-lymphangiogenic signaling during tumor development reduces cell spread to sentinel lymph nodes (SLNs). However, it is uncl...

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Detalles Bibliográficos
Autores principales: Gogineni, Alvin, Caunt, Maresa, Crow, Ailey, Lee, Chingwei V., Fuh, Germaine, van Bruggen, Nicholas, Ye, Weilan, Weimer, Robby M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3712991/
https://www.ncbi.nlm.nih.gov/pubmed/23874750
http://dx.doi.org/10.1371/journal.pone.0068755