Functional Polymorphisms in the CYP2C19 Gene Contribute to Digestive System Cancer Risk: Evidence from 11,042 Subjects

BACKGROUND: CYP2C19 belongs to the cytochrome P450 superfamily of enzymes involved in activating and detoxifying many carcinogens and endogenous compounds, which has attracted considerable attention as a candidate gene for digestive system cancer. CYP2C19 has two main point mutation sites (CYP2C19*2...

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Detalles Bibliográficos
Autores principales: Zhou, Bo, Song, Zhenshun, Qian, Mingping, Li, Liang, Gong, Jian, Zou, Shaowu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3712993/
https://www.ncbi.nlm.nih.gov/pubmed/23874401
http://dx.doi.org/10.1371/journal.pone.0066865

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3712993/
https://www.ncbi.nlm.nih.gov/pubmed/23874401
http://dx.doi.org/10.1371/journal.pone.0066865

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