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Single Point Mutations Result in the Miss-Sorting of Glut4 to a Novel Membrane Compartment Associated with Stress Granule Proteins

Insulin increases cellular glucose uptake and metabolism in the postprandial state by acutely stimulating the translocation of the Glut4 glucose transporter from intracellular membrane compartments to the cell surface in muscle and fat cells. The intracellular targeting of Glut4 is dictated by speci...

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Detalles Bibliográficos
Autores principales: Song, XiaoMei, Lichti, Cheryl F., Townsend, R. Reid, Mueckler, Mike
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3713040/
https://www.ncbi.nlm.nih.gov/pubmed/23874650
http://dx.doi.org/10.1371/journal.pone.0068516